Symptoms are associated with atrophy patterns in Alzheimer disease (AD).

 
   Lead Investigator:    Jo Barnes
   Institution      :    UCL Institute of Neurology, London
   E-Mail           :    j.barnes@ucl.ac.uk
   Proposal ID      :    474


   Publications:


1  Barnes J, Bartlett JW, Wolk DA, van der Flier WM, Frost C
   Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease
   Journal Article  J Alzheimers Dis,64:631-642,2018,PMC6207933

   PUBLISHED





   Proposal Description:
   Overarching aim: To determine structural atrophy correlates of first predominant and first visit cognitive and behavioural symptoms in AD  A) What are the atrophy-pattern correlates of first predominant cognitive, and first predominant behavioural symptom, in AD? Are any findings independent of age, gender, head size, and in the subset in whom it is measured, APOE e4?  B) What are the atrophy-pattern correlates of first visit cognitive and first visit behavioural symptoms in AD? Are any findings independent of age, gender, head size, and first predominant cognitive or behavioural symptom and in the subset in whom it is measured, APOE e4?